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Downard KM (2004) Mass Spectrometry - A Foundation Course, Royal Society of Chemistry, Cambridge UK (ISBN 978-0-85404-609-6)


About this book:

Mass Spectrometry: A Foundation Course is a textbook covering the field of mass spectrometry across the chemical, physical, biological, medical and environmental sciences. Sufficient depth is provided for the reader to appreciate the reasons behind and basis for particular experiments. It is uniquely and logically organised to enable the book to form the basis for a university course in mass spectrometry at the undergraduate or postgraduate level. This is achieved by combining specific core sections coupled to optional areas of study tailored to students of the chemical, physical, biological, medical and environmental sciences. Recommended course structures are provided in the front of the book. Dedicated chapters are included on: organic mass spectrometry; ion chemistry - to emphasise the role of mass spectrometry in fundamental chemistry and physics; biological mass spectrometry including proteomics; mass spectrometry in medicine, environmental and surface science and accelerator mass spectrometry, to emphasise the importance of these areas. Each chapter concludes with key references and additional recommended reading material, making the book an excellent springboard to further study. Highly readable, easy-to-use and logically presented, Mass Spectrometry: A Foundation Course is an ideal text for students and for those who work with mass spectrometers who wish to gain a solid understanding of the basics in modern mass spectrometry.



"Mass Spectrometry: A Foundation Course" accomplishes its goal with very few shortcomings ... A text that does an exceptional job of introducing MS in a clearly written and logical fashion with sufficient depth for its intended audience of either undergraduate or graduate students ... Kevin Downard has produced an excellent book, well-suited to the diverse audience he envisions ... certainly I will be recommending it to both undergraduates and graduates seeking an introduction to MS" Trends in Analytical Chemistry, February 2005 (Professor Charles Wilkins)
"I recommend this book highly to anyone looking for a first port of call on the journey to mass spectrometry"  Cancer Scienceboard Net, 20 December 2004 (Dr Oliver Bogler)
"A basis for instruction of undergraduate and new postgraduate students". Chemistry World, April 2005 (Professor Tony Mallet)
"A single text volume that is clear, uncluttered, concise and systematic. This book should find ready adoption in courses which focus on teaching of MS."  Mass Spectrometry Reviews, (Professor Philip Marriott) *
"Written in a highly readable and entertaining style. Overall this book is very useful and can be recommended as an introduction for students into the presently wide applicability of mass spectrometry to a variety of disciplines." Australian Journal of Chemistry, 2005 (late Emeritus Professor Nico Nibbering)
"This book should find ready adoption in courses which focus on teaching of MS, and it appears to be one of the better teaching texts in MS." Physical Sciences Educational Reviews, June 2005 (Professor Philip Marriott)

"A Great Book for Students of Mass Spec. This is an e-z to read book with all the basics of mass spectrometry and advanced applications. Unlike others you can actually understand why mass specs are built and operated they way there are, and there are plenty of good illustrations. There's a really good section on proteomics and medicial applications are also covered. I didn't know they took mass specs to mars! The history section was helpful to me in order to put the field in context. I'd recommend it to any student of mass spec or someone else who wants to get a great overview."  24 October 2004 -


Downard KM ed. (2007) Mass Spectrometry of Protein Interactions, John Wiley & Sons, New Jersey U.S.A. (ISBN 978-0-471-79373-1)


About this book:

The authoritative (and the first published) book on analyzing protein interactions by mass spectrometry. Mass spectrometry (MS) is playing an increasingly important role in the study of protein interactions. Mass Spectrometry of Protein Interactions presents timely and definitive discussions of the diverse range of approaches for studying protein interactions by mass spectrometry with an extensive set of references to the primary literature. Each chapter is written by authors or teams of authors who are international authorities in their fields. This leading reference text discusses the direct detection of protein interactions through electrospray ionization (ESI-MS), ion mobility analysis, and matrix-assisted laser desorption/ionization (MALDI-MS) and covers the indirect analysis of protein interactions through hydrogen-deuterium exchange (HX-MS), limited proteolysis, cross-linking and radial probe (RP-MS) protein footprinting. It guides researchers in the use of mass spectrometry in structural biology, biochemistry, and protein science to map and define the huge number and diversity of protein interactions and reviews the latest discoveries and applications and addresses new and ongoing challenges. This is a comprehensive reference for researchers in academia and industry engaged in studies of protein interactions and an excellent text for graduate and postgraduate students.



"The contributions are written in a concise style and highlight the state of the art in the respective methodologies, but also point out shortcomings and challenges. Each chapter serves as an extensive resource of references to the primary literature. If applicable, suitable software packages for the support of the data analysis are indicated. The book is an excellent read for graduate students and researchers in industry and academia who are interested in learning more about the current status of mass‐spectrometry‐based protein‐interaction analysis." ChemBioChem, March 2008 (Dr. Jürgen Cox. Max‐Planck Institute)


a limited supply of signed copies of these texts are available at a discount directly from the author