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Downard Laboratory WWW site

Publications                       to request a complimentary PDF copy of any laboratory publication, send an email to:  kevchem @ mail.com

 

Journal articles (2017-present)                       full list of ~140 publications :          1988 - present  (orcid ID record)

 

 

Downard KM (2023) Rapid Detection and Evolution of SARS-CoV-2 and other Viruses with High Resolution Mass Spectrometry, in Detection and Analysis of Microorganisms by Mass Spectrometry - New Developments in Mass Spectrometry, Ed. L. Qiao, Royal Society of Chemistry, Cambridge UK, in press.

 

Mann C, Hoyle JS, Downard KM (2022) Detection of SARS-CoV2 Coronavirus Omicron Variant with Mass Spectrometry, Analyst, 147: 1181-1190.  http://dx.doi.org/10.1039/d2an00028h

 

Mann C, Downard KM (2022) Analysis of Bacterial Biotyping Datasets with a Mass Based Phylonumerics Approach, Anal. Bioanal. Chem., 414: 3411- 3417.   https://doi.org/10.1007/s00216-022-03961-4

 

Downard KM (2022) Building Australia's First Mass Spectrometer. Recognizing the Achievements of J. Roger Bird, J. Mass Spectrom., e4887.   https://doi.org/10.1002/jms.4887

 

Downard KM (2022) J. Roger Bird and Australia's First Mass Spectrometer, Aust. Physics, 59(3): 15-18.   https://aip.org.au/page-18243

 

Mann C, Downard KM (2022) Evolution of SARS-CoV2 Coronavirus Surface Protein Investigated with Mass Spectrometry Based Phylogenetics, Anal. Lett.  55: 305-317.   http://dx.doi.org/10.1080/00032719.2021.1928685

 

Downard KM (2022) Sequence Free Phylogenetics with Mass Spectrometry, Mass Spectrom. Rev., 41: 3-14. https://doi.org/10.1002/mas.21658

 

Mann C, Griffin JH, Downard KM (2021) Detection and Evolution of SARS-CoV2 Coronavirus Variants of Concern with Mass Spectrometry, Anal. Bioanal. Chem., 413: 7241-7249.   http://dx.doi.org/10.1007/s00216-021-03649-1

 

Downard KM (2021) Joseph John Thomson Investigates the Paranormal (Historical Perspective), Eur. J. Mass Spectrom., 27: 151-157.   http://dx.doi.org/10.1177/14690667211050599

 

Griffin JH, Downard KM (2021) Mass Spectrometry Analytical Responses to the SARS-CoV2 Coronavirus in Review, Trends Anal. Chem. 142: 116328.  https://doi.org/10.1016/j.trac.2021.116328

 

Downard KM (2021) Protein Phylogenetics with Mass Spectrometry. A Comparison of Methods, Anal. Methods, 13, 1442-1454.   https://doi.org/10.1039/d1ay00153a

 

Akand EH, Downard KM (2021) Evolution of Type B Influenza Virus using a Mass Spectrometry Based Phylonumerics Approach, Evol. Biol.  48: 259-268.  https://dx.doi.org/10.1007/s11692-021-09535-z

 

Dollman NL, Griffin JH, Downard KM (2020) Detection, Mapping and Proteotyping of SARS CoV-2 Coronavirus with High Resolution Mass Spectrometry, ACS Infect. Dis., 6: 3269-3276.   https://dx.doi.org/10.1021/acsinfecdis.0c00664

 

Downard (2020) Darwin's Tree of Life is Numbered. Resolving the Origins of Species by Mass, Evol. Bio., 47: 325-333.   https://doi.org/10.1007/s11692-020-09517-7

 

Akand EH, Downard KM (2020) Reimaging the Tree of Life using a Mass Based Phylonumerics Approach, Evol. Biol. 47: 76-84. https://doi.org/10.1007/s11692-020-09490-1

 

Downard KM (2020) Mass-based Protein Phylogenetic Approach to Identify Epistasis, in Methods in Molecular Biology: Epistasis - Methods and Protocols (Ed. K-C Wong), Ch. 1, pp. 1-17, Springer NY USA.   https://www.springer.com/gp/book/9781071609460

 

Akand EH, Downard KM (2019) Mechanisms of Antiviral Resistance in Influenza Neuraminidase Revealed by a Mass Spectrometry Based Phylonumerics Approach, Mol. Phylogen. Evol. 135: 286-296.   https://doi.org/10.1016/j.ympev.2019.03.009

 

Downard KM (2019) Concentration of Hydroxyl Radicals during Electrical Discharge for Radical Probe Protein Footprinting Mass Spectrometry, Rapid Commun. Mass Spectrom. 33: 1420-1422.   https://doi.org/10.1002/rcm.8484

 

Downard KM, Maleknia SD (2019) Mass Spectrometry in Structural Proteomics: The Case for Radical Probe Protein Footprinting, Trends in Anal. Chem., 110: 293-302.   https://doi.org/10.1016/j.trac.2018.11.016     PDF copy for download

 

Downard KM (2019) A Molecular Immunoproteomics Approach to Assess the Viral Antigenicity of Influenza, in Methods in Molecular Biology: Immunoproteomics, 2nd edition (Ed. S. Twine & K. Fulton), Vol. 2024, Ch. 24, pp. 353-369.   https://doi.org/10.1007/978-1-4939-9597-4_24

 

Maleknia SD, Downard KM (2019) Protein Footprinting with Radical Probe Mass Spectrometry - Two Decades of Achievement, in Current Perspectives on Footprinting as a Tool for Structural Biology (ed. Ralston CY),  Protein Peptide Letters, 26(1):  4-15.  https://doi.org/10.2174/0929866526666181128124241

 

Akand EH, Downard KM (2018) Ancestral and Compensatory Mutations that Promote Antiviral Resistance in Influenza N1 Neuraminidase Revealed by a Phylonumerics Approach, J. Mol. Evol., 86(8): 546-553.   https://doi.org/10.1007/s00239-018-9866-4

 

Uddin R, Downard KM (2018) Molecular Basis of Benzimidazole Inhibitors to Hepatitis C Virus Envelope Glycoprotein, Chem. Biol. Drug Design, 92(3): 1638-1646. (cover article)   https://doi.org/10.1111/cbdd.13329

 

Akand EH, Downard KM (2018) Identification of Epistatic Mutations and Insights into the Evolution of the Influenza Virus Using a Mass-Based Protein Phylogenetic Approach, Mol. Phylogenet. Evol., 121: 132-138.   http://dx.doi.org/10.1016/j.ympev.2018.01.009

 

Cody RB, Tamura J, Downard KM (2018) Quantitation of Anthocyanins in Elderberry Fruit Extracts and Nutraceutical Formulations with Paper Spray Ionization Mass Spectrometry, J. Mass Spectrom., 53: 58-64.  http://www.dx.doi.org/10.1002/jms.4033

 

Akand EH, Downard KM (2017) Mutational Analysis Employing a Phylogenetic Mass Tree Approach in a Study of the Evolution of the Influenza Virus, Mol. Phylogenet. Evol., 112: 209-217.  http://dx.doi.org/10.1016/j.ympev.2017.04.005

 

Uddin R, Downard KM (2017) Subtyping of Hepatitis C Virus with High Resolution Mass Spectrometry, Clin. Mass Spectrom., 4-5: 19-24.   http://dx.doi.org/10.1016/j.clinms.2017.08.003

 

Ma S, Downard KM, Wong JWH (2017) Phylogenetic Analysis using Protein Mass Spectrometry, in Methods in Molecular Biology: Proteome Bioinformatics (eds. Mathivanan S, Keerthikumar S), Humana Press, NJ USA, pg. 135-146. (ISBN 978-1-4939-6738-4).   http://www.springer.com/gp/book/9781493967384

 

 

Books

 

Downard KM ed. (2007) Mass Spectrometry of Protein Interactions, John Wiley & Sons, New Jersey U.S.A. (ISBN 978-0-471-79373-1)  http://au.wiley.com/WileyCDA/WileyTitle/productCd-0471793736.html

 

Downard KM (2004) Mass Spectrometry - A Foundation Course, Royal Society of Chemistry, Cambridge UK (ISBN 978-0-85404-609-6)  http://www.rsc.org/shop/books/2004/9780854046096.asp

 

 

For articles on the early History of Mass Spectrometry, click here