SARS-CoV2 MS Publications


This laboratory led Australia's response to the SARS-CoV2 virus with mass spectrometry since 2020. We have developed and applied our approaches to detect SARS-CoV2 virus, resolve and distinguish its sub-variants and identify recombinant forms, in clinical specimens. We have also reviewed MS based approaches for doing so, including many from new entrants to the field, in the first comprehensive review of the subject (TrAC 2021). Our expertise in the detection and characterisation of viruses with MS, and particularly respiratory viruses, for over 25 years, has catalysed this research.  Follow this link for a full list of publications describing our virus research.


SARS-CoV2 journal articles (2020-present)



Lanyon HE, Todd BP, Downard KM (2023) Distinguishing Common SARS-CoV2 Omicron and Recombinant Variants with High Resolution Mass Spectrometry, Analyst: 148, 6306-6314.


Downard KM (2023) 25 Years Responding to Respiratory and Other Viruses with Mass Spectrometry, Mass Spectrom. (Tokyo), 12: A0136.


Hoyle JS, Downard KM (2023) High Resolution Mass Spectrometry of Respiratory Viruses. Next Generation Viral Typing, Subtyping, Variant and Sub- Variant Identification, Analyst, 148: 4263-4273.


Hoyle JS, Mann C, Akand EH, Downard KM (2023) Charting and Tracking the Evolution of the SARS CoV-2 Coronavirus Variants of Concern with Protein Mass Spectrometry, Analyst, 148, 2834-2843.


Lanyon H, Hoyle JS, Downard KM (2023) Resolving Omicron Sub-Variants of SARS CoV-2 Coronavirus with MALDI Mass Spectrometry, Analyst, 148: 966-972.


Downard KM (2023) Rapid Detection and Evolution of SARS-CoV-2 and other Viruses with High Resolution Mass Spectrometry, in Detection and Analysis of Microorganisms by Mass Spectrometry - New Developments in Mass Spectrometry, Ed. L. Qiao, Royal Society of Chemistry, Cambridge UK, in press.


Mann C, Hoyle JS, Downard KM (2022) Detection of SARS-CoV2 Coronavirus Omicron Variant with Mass Spectrometry, Analyst, 147: 1181-1190.


Mann C, Downard KM (2022) Evolution of SARS-CoV2 Coronavirus Surface Protein Investigated with Mass Spectrometry Based Phylogenetics, Anal. Lett.  55: 305-317.


Mann C, Griffin JH, Downard KM (2021) Detection and Evolution of SARS-CoV2 Coronavirus Variants of Concern with Mass Spectrometry, Anal. Bioanal. Chem., 413: 7241-7249.


Griffin JH, Downard KM (2021) Mass Spectrometry Analytical Responses to the SARS-CoV2 Coronavirus in Review, Trends Anal. Chem. 142: 116328.


Dollman NL, Griffin JH, Downard KM (2020) Detection, Mapping and Proteotyping of SARS CoV-2 Coronavirus with High Resolution Mass Spectrometry, ACS Infect. Dis., 6: 3269-3276.



© 2018-2023 Downard Research Laboratory. All rights reserved.