SARS-CoV2 MS Publications
This laboratory led Australia's response to the SARS-CoV2 virus with mass spectrometry since 2020. We have developed and applied our approaches to detect SARS-CoV2 virus, resolve and distinguish its sub-variants and identify recombinant forms, in clinical specimens. We have also reviewed MS based approaches for doing so, including many from new entrants to the field, in the first comprehensive review of the subject (TrAC 2021). Our expertise in the detection and characterisation of viruses with MS, and particularly respiratory viruses, for over 25 years, has catalysed this research. Follow this link for a full list of publications describing our virus research.
SARS-CoV2 journal articles (2020-present)
Lanyon HE, Todd BP, Downard KM (2023) Distinguishing Common SARS-CoV2 Omicron and Recombinant Variants with High Resolution Mass Spectrometry, Analyst: 148, 6306-6314. https://doi.org/10.1039/D3AN01376F
Downard KM (2023) 25 Years Responding to Respiratory and Other Viruses with Mass Spectrometry, Mass Spectrom. (Tokyo), 12: A0136. https://doi.org/10.5702/massspectrometry.A0136
Hoyle JS, Downard KM (2023) High Resolution Mass Spectrometry of Respiratory Viruses. Next Generation Viral Typing, Subtyping, Variant and Sub- Variant Identification, Analyst, 148: 4263-4273. https://doi.org/10.1039/d3an00953j
Hoyle JS, Mann C, Akand EH, Downard KM (2023) Charting and Tracking the Evolution of the SARS CoV-2 Coronavirus Variants of Concern with Protein Mass Spectrometry, Analyst, 148, 2834-2843. https://doi.org/10.1039/d3an00614j
Lanyon H, Hoyle JS, Downard KM (2023) Resolving Omicron Sub-Variants of SARS CoV-2 Coronavirus with MALDI Mass Spectrometry, Analyst, 148: 966-972. https://doi.org/10.1039/D2AN01843H
Downard KM (2023) Rapid Detection and Evolution of SARS-CoV-2 and other Viruses with High Resolution Mass Spectrometry, in Detection and Analysis of Microorganisms by Mass Spectrometry - New Developments in Mass Spectrometry, Ed. L. Qiao, Royal Society of Chemistry, Cambridge UK, in press. https://books.rsc.org/books/edited-volume/2122/Detection-and-Analysis-of-Microorganisms-by-Mass
Mann C, Hoyle JS, Downard KM (2022) Detection of SARS-CoV2 Coronavirus Omicron Variant with Mass Spectrometry, Analyst, 147: 1181-1190. http://dx.doi.org/10.1039/d2an00028h
Mann C, Downard KM (2022) Evolution of SARS-CoV2 Coronavirus Surface Protein Investigated with Mass Spectrometry Based Phylogenetics, Anal. Lett. 55: 305-317. http://dx.doi.org/10.1080/00032719.2021.1928685
Mann C, Griffin JH, Downard KM (2021) Detection and Evolution of SARS-CoV2 Coronavirus Variants of Concern with Mass Spectrometry, Anal. Bioanal. Chem., 413: 7241-7249. http://dx.doi.org/10.1007/s00216-021-03649-1
Griffin JH, Downard KM (2021) Mass Spectrometry Analytical Responses to the SARS-CoV2 Coronavirus in Review, Trends Anal. Chem. 142: 116328. https://doi.org/10.1016/j.trac.2021.116328
Dollman NL, Griffin JH, Downard KM (2020) Detection, Mapping and Proteotyping of SARS CoV-2 Coronavirus with High Resolution Mass Spectrometry, ACS Infect. Dis., 6: 3269-3276. https://dx.doi.org/10.1021/acsinfecdis.0c00664
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